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Product Details

Delayed release capsules for the treatment of major depressive disorder; generalized Anxiety Disorder; Diabetic Peripheral Neuropathy; and Chronic Musculoskeletal Pain. Can help relieve nerve pain in patients with diabetes, chronic back pain, arthritis, or fibromyalgia.

Duloxetine delayed-release capsules, USP (duloxetine hydrochloride) is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI) for oral administration. Its chemical designation is (+)-(S)-N-methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine hydrochloride. The empirical formula is C18H19NOS∙HCl, which corresponds to a molecular weight of 333.88.

Indications and Usage

Duloxetine delayed-release capsules are a serotonin and norepinephrine reuptake inhibitor (SNRI) indicated for:

1. Major Depressive Disorder (MDD)
2. Generalized Anxiety Disorder (GAD)
3. Diabetic Peripheral Neuropathic Pain (DPNP)
4. Chronic Musculoskeletal Pain

Dosage and Administration

Take Duloxetine hydrochloride delayed release capsules once daily, with or without food. Swallow the capsule whole, do not crush or chew. Take a missed dose as soon as it is remembered. Do not take two doses of at the same time. Dosage may be specific to disorder being treated.

Information for the Patient

Read information on Medication Guide to be informed about the benefits and risks associated with treatment with Duloxetine delayed-release capsules and counsel them in its appropriate use. A patient Medication Guide is available for Duloxetine delayed-release capsules.Alert your prescriber if Suicidal Thoughts or Behavior issues occur while taking Duloxetine delayed-release capsules.While patients may notice improvement with Duloxetine delayed-release capsules therapy in 1 to 4 weeks, advise patients to continue therapy as directed.

Warnings

Read Drug Label Information for complete list of warnings and precautions. Which may include Suicidal Thoughts and Behaviors; Hepatotoxicity, Orthostatic Hypotension, Falls and Syncope; Serotonin Syndrome; Abnormal Bleeding; Severe Skin Reactions; Discontinuation of Treatment; Activation of Mania/Hypomania; Angle-Closure Glaucoma; Seizures; Effect on Blood Pressure; Hyponatremia; Urinary Hesitation and Retention. Consult your healthcare provider immediately if you experience any adverse reactions.